April 1, 2001,

The Prime Minister, 
The Rt. Hon. Tony Blair, 
10 Downing Street,

Your fax no.: 7925-0918

Dear Mr. Blair,

The foot and mouth disease (FMD) epidemic in Britain has appalled the public, the scientific and farming communities in its rapid spread, the ever increasing number of cases, the insufficiency of the measures taken to contain it, and above all the enormous slaughter of healthy animals carried out by the authorities. One of the weapons against FMD that could be used is vaccination, and the argument against this has been that once vaccinated, the animal population could harbor the disease without it being detected. 

This argument is simply not true, and the British public have not been informed of the scientific state of play in this area. Last week's issue of the prestigious scientific journal Science ran an article describing the epidemic, and supported the work of Shen and colleagues:
(Shen, F, Chen, PD, Walfield, AM, Ye, J., House, J., Brown, F and Wang, CY. Differentiation of convalescent animals from those vaccinated against FMD by a peptide ELISA. Vaccine 17: (1999) 3039-3049).

These workers described a test they developed in which they selected a piece, or a peptide, of the viral non-structural protein to act as the antigen in an immunological test run in microwell plates. This test was invariably positive when the serum of diseased animals was tested, and negative when the serum of vaccinated animals was used. They tested sheep, goats and cattle with all 7 strains of FMD. 

The test is marketed by:
United Biomedical Inc, 25 Davids Drive,Hauppauge NY 11788, USA.

I understand that these scientists have offered their tests to MAFF, and have been refused. In the face of national disaster, it is evident that we have to move on and realise that the methods of 1967 may not be valid today; and that science is constantly developing new tools for the solution of problems in every area of human effort; and that failure to recognise and utilise these new tools is at our own expense. Once the national animal population is vaccinated to a high proportion, the disease will not have a reservoir of susceptible animals to infect.! 

The exportation of British livestock will still be safe as the exported animals can be tested by Shen's technique. These opinions are my own and do not reflect those of the medical college to which I am attached.

Sincerely,

Dr. Robert Dourmashkin, 
40 Lucerne Road, 
Highbury, 
London,
N5 1TZ.

At:
Section of Academic Virology,
St Barts and Royal London Medical School ,
Whitechapel,
 E1 2AD

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