Letter from Prof Fred Brown,
United States Department of Agriculture,
Plum Island Animal Disease Center,
Greenport,
NY

To:	 The Countess Mar

Dear Margaret,

If you are going to pursue your interest in foot-and-mouth disease, here are a few facts you may wish to consider.

1. Infected animals can be distinguished from vaccinated animals by a simple test of their blood -- see the reprint I sent to you.

2. If a vaccinated animal becomes infected it can be identified by the test described in 1.

3. If the animals in 2. become infected and then become carrier animals it is extremely unlikely that they would pass on the virus to other animals. Many attempts to infect naive animals by bringing them into contact with carrier animals have failed. There is, as far as I know, just one reported case.

If it is decided to ring vaccinate, this would reduce the virus load enormously. In addition it would be ludicrous to slaughter the vaccinated animals subsequently.

All the rules about moving animals following vaccination are based on the information available before differential diagnostic tests had been devised. These rules need serious debate.

All good wishes,
Yours sincerely,

Fred Brown, FRS,
United States Department of Agriculture,
Plum Island Animal Disease Center,
Greenport,
NY
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